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live fast die hard meaning — Court Rules in Favor of Heron in Patent Lawsuit Against Fresenius Kabi USA , LLC — SAN DIEGO , Dec. 3, 2024 /PRNewswire/ -- Heron Therapeutics, Inc. (Nasdaq: HRTX) ("Heron" or the "Company"), a commercial-stage biotechnology company, today announced that the U.S. District Court for the District of Delaware ruled in Heron's favor in the Company's patent litigation against Fresenius Kabi USA , LLC with respect to CINVANTI® (aprepitant) injectable emulsion. The district court found that Heron's U.S. Patent Nos. 9,561,229 and 9,974,794, which expire in 2035, are valid and would be infringed by Fresenius' proposed generic product. The district court decision concludes the litigation initiated in July 2022 in response to Fresenius' submission of an Abbreviated New Drug Application with the U.S. Food and Drug Administration seeking approval of a generic version of CINVANTI®. As a result of the decision, Heron will seek an order from the Court prohibiting Fresenius from launching its generic CINVANTI® until after the expiration of the patents in 2035. This decision is subject to appeal. "We are pleased with this anticipated result of the proceeding and will continue to vigorously defend the CINVANTI® patent estate in the future," said Craig Collard, Chief Executive Officer of Heron. "The team at Heron takes great pride in the result of our successful history of developing injectable products, which is demonstrated by the strength of our intellectual property and the performance of our innovative drugs like CINVANTI® in serving patients with serious unmet needs." About Heron Therapeutics, Inc. Heron Therapeutics, Inc. is a commercial-stage biotechnology company focused on improving the lives of patients by developing and commercializing therapeutic innovations that improve medical care. Our advanced science, patented technologies, and innovative approach to drug discovery and development have allowed us to create and commercialize a portfolio of products that aim to advance the standard-of-care for acute care and oncology patients. For more information, visit www.herontx.com . Forward-looking Statements This news release contains "forward-looking statements" as defined by the Private Securities Litigation Reform Act of 1995. Heron cautions readers that forward-looking statements are based on management's expectations and assumptions as of the date of this news release and are subject to certain risks and uncertainties that could cause actual results to differ materially. Therefore, you should not place undue reliance on forward-looking statements. Important factors that could cause actual results to differ materially from those in the forward-looking statements are set forth in our most recent Annual Report on Form 10-K and any subsequent Quarterly Reports on Form 10-Q, and in our other reports filed with the Securities and Exchange Commission, including under the caption "Risk Factors." Forward-looking statements reflect our analysis only on their stated date, and Heron takes no obligation to update or revise these statements except as may be required by law. Investor Relations and Media Contact: Ira Duarte Executive Vice President, Chief Financial Officer Heron Therapeutics, Inc. iduarte@herontx.com 858-251-4400 View original content to download multimedia: https://www.prnewswire.com/news-releases/us-district-court-upholds-validity-of-cinvanti-patents-302321651.html SOURCE Heron Therapeutics, Inc.NoneState Senator Marie Alvarado-Gil Compares Senate Majority Leader to KKK ‘Grand Wizard’

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The Chicago Cubs added starter Matthew Boyd to their rotation on a two-year deal. The signing could mean one of the Cubs' starters from last season could be out of a job, and resultingly traded. FanSided's Jordan Campbell noted that the signing of Boyd could mean the Cubs may have to move on from Javier Assad. Assad made 29 starts last season and could be included in a trade for a high-end starter. "Javier Assad continued to defy expectations during the 2024 season. In 29 starts with the Cubs last season, Assad posted a 3.73 ERA. It was an impressive season for Assad, no doubt, but his expected ERA of 4.97 and expected FIP of 4.61 do suggest there was a tremendous amount of luck involved with his success," wrote Campbell. "Assuming the Cubs look to the trade market to add a high-end starting pitcher, Assad could be included as part of the package going the other way." Assad posted the best ERA of his young career after his first full season as a starter. The Cubs clearly want to beef up their rotation. Adding Boyd is a good start, but they could go after a star as well. Garrett Crochet is on the trade block and the Cubs could include Assad in a deal for him. Assad will not be a free agent until 2029 and could be an attractive trade target. The Cubs signed Boyd to a two-year, $29 million deal. Boyd has played in just 23 games in the last two seasons so the Cubs may want to hang on to Assad. More MLB: Matthew Boyd signing could mean Cubs dump young pitcher following career year

Woman Says She Walked Out of a First Date After the Guy’s Mom Showed Up: ‘I Couldn’t Take It’Democrats stick with Schumer as leader. Their strategy for countering Trump is far less certain

Trump’s DEA nominee withdraws from consideration just days after being pickedWASHINGTON — The House shut down Democrats' efforts Thursday to release the long-awaited ethics report into former Rep. Matt Gaetz, pushing the fate of any resolution to the yearslong investigation of sexual misconduct allegations into further uncertainty. The nearly party-line votes came after Democrats had been pressing for the findings to be published even though the Florida Republican left Congress and withdrew as President-elect Donald Trump’s nominee for attorney general. Rep. Tom McClintock, R-Calif., was the sole Republican to support the effort. Most Republicans have argued that any congressional probe into Gaetz ended when he resigned from the House. Speaker Mike Johnson also requested that the committee not publish its report, saying it would be a terrible precedent to set. While ethics reports have previously been released after a member’s resignation, it is extremely rare. Shortly before the votes took place, Rep. Sean Casten, D-Ill., who introduced one of the bills to force the release, said that if Republicans reject the release, they will have “succeeded in sweeping credible allegations of sexual misconduct under the rug.” Gaetz has repeatedly denied the claims. Earlier Thursday, the Ethics panel met to discuss the Gaetz report but made no decision, saying in a short statement that the matter is still being discussed. It's unclear now whether the document will ever see the light of day as lawmakers have only a few weeks left before a new session of Congress begins. It's the culmination of weeks of pressure on the Ethics committee's five Republicans and five Democrats who mostly work in secret as they investigate allegations of misconduct against lawmakers. The status of the Gaetz investigation became an open question last month when he abruptly resigned from Congress after Trump's announcement that he wanted his ally in the Cabinet. It is standard practice for the committee to end investigations when members of Congress depart, but the circumstances surrounding Gaetz were unusual, given his potential role in the new administration. Rep. Michael Guest, R-Miss., the committee chairman, said Wednesday that there is no longer the same urgency to release the report given that Gaetz has left Congress and stepped aside as Trump's choice to head the Justice Department. “I’ve been steadfast about that. He’s no longer a member. He is no longer going to be confirmed by the Senate because he withdrew his nomination to be the attorney general,” Guest said. The Gaetz report has also caused tensions between lawmakers on the bipartisan committee. Pennsylvania Rep. Susan Wild, the top Democrat on the panel, publicly admonished Guest last month for mischaracterizing a previous meeting to the press. Gaetz has denied any wrongdoing and said last year that the Justice Department’s separate investigation against him into sex trafficking allegations involving underage girls ended without federal charges. His onetime political ally Joel Greenberg, a fellow Republican who served as the tax collector in Florida’s Seminole County, admitted as part of a plea deal with prosecutors in 2021 that he paid women and an underage girl to have sex with him and other men. The men were not identified in court documents when he pleaded guilty. Greenberg was sentenced in late 2022 to 11 years in prison.Trump says hush money case should be thrown out after Hunter Biden pardon

Justice Department announces sweeping reforms to curb suicides in federal prisons and jailsThe Broncos are going young at wide receiver. Denver waived wide receiver Josh Reynolds on Tuesday, according to the league’s transaction wire. Reynolds broke his finger catching a touchdown Week 5 against Las Vegas and needed minor surgery, landing him on injured reserve. While he was out, Reynolds was shot twice in an incident during which he and two others had their vehicle shot at more than 30 times i . Reynolds also watched as several young Denver wide receivers — notably rookies Devaughn Vele and Troy Franklin — saw the field more and more and got more comfortable. Now Reynolds will be on waivers for a day and any team can claim him for the stretch run of the season. Tuesday marked the final day of Reynolds’ 21-day practice window, meaning Denver either had to reinstate him to the 53-man roster, have him revert to injured reserve (which would end his season) or waive him. They chose to waive him and move forward with the group of receivers that’s been playing the past several weeks. Reynolds caught 12 passes for 198 yards and a touchdown in his brief Broncos tenure. Reynolds signed a two-year, $9 million deal this spring that came with a $2 million signing bonus and $4.25 million in total guarantees. Waiving him will clear $4.5 million in space on the Broncos’ 2025 salary cap and leave a $1 million dead cap charge for 2025.

Emmanuel Macron rolled the dice and came up snake eyes. The French president took a big gamble six months ago, when he hoping to stem the growing power of the extreme right. But that decision appeared to backfire this week, when and thus the entire Cabinet for the first time in decades. The inciting complaints included a distasteful budget, narrow tax increases and belt-tightening. But the real issues run far deeper. Ever since his arrival in office more than seven years ago, Macron has made it his mission to reform an ancestral French system that few of his voters seem to want to change. His two predecessors — and the — expended enormous political capital simply tinkering around the edges and ended up with one-term presidencies. Macron has had more success, far-right opponent Marine Le Pen, but largely because not enough French people are yet willing to turn their nation over to someone with ties to . The French people protested en masse when Macron sought to to force an unwelcome move toward green energy — but they returned him to office. Now term-limited, he started to try to turn up the heat on reform. Back into the streets went voters after Macron sought to raise the notoriously low retirement age from 62 to 64. Such a move could have helped , where it has so long been mired. But there was still the question of a ballooning budget deficit and national debt. By choosing Michel Barnier to be his prime minister, Macron apparently felt he could finesse his problems with both the far right and the far left by choosing a neutral technocrat. But in France’s deeply polarized atmosphere, this compromise attempt did not work. As Macron has now experienced, the middle of the road is where folks in France simply get run over. Macron is known for his pitch-perfect political skills. But he seems to have misjudged the broad drift to the right sweeping across Europe. Germany will have its , after the neo-fascist AfD swept local elections. In Romania, on Friday, two days before the second round of presidential elections, the nation’s constitutional court suddenly annulled the entire vote. of World War II and self-described Vladimir Putin acolyte took first place in the first round following by Kremlin allies. The French by and large recognize they are poised on the lip of a deep abyss — politically and financially — with few good routes back. The hardly united opposition has never agreed on much of anything except its distaste for Macron and his (sometimes ) methods. In his first speech to the nation following his government’s collapse, Macron offered little beyond “the need to work together for France,” and a promise to find another prime minister. He also suggested that a new government budget might not be cobbled together before the end of the year, proposing instead a continuing resolution like in the United States. Simply put, Macron has overreached, overplayed his hand and, though perhaps more adept than his predecessors, may well have to pay a similar price. Unable to bend the unbending French people to their will, these former presidents were each forced into a retirement bereft of influence. They left behind terms with few accomplishments. And the French people will likely be the ultimate victims — of higher taxes and an increasingly threadbare existence. In an overnight , a very slim majority of French voters approved of the no-confidence vote. But more than 80% feared for the future of France, its , which has now surpassed Greece, Italy and Spain. But this weekend, Macron will have another chance to try to reassure his anxious citizens and reclaim a degree of the political capital he has squandered. On Sunday, he presides over the grand unveiling of France’s landmark Notre Dame Cathedral — destroyed in a 2019 fire, now reborn. and pledged what many at the time considered an impossible task — to rebuild the shattered landmark in five years. And it was done. Now, surrounded by 50 heads of state, including and soon-to-be counterpart President-elect Donald Trump, Macron will lead a ceremony every French voter will be watching with delight and awe. Will it be enough?